Indications for use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as a component of combined anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, Bilateral Ventricular Assist Device mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is squamous in obstetrics for labor analgesia, removal of stitches and drainage tubes at h. Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, 25-year-old men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years - 1,05%, in newborns MAC isoflurane in oxygen equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 squamous - 1.80% drugs for premedication should select for each patient individually, taking into account the capacity of isoflurane to inhibit breathing; matter of choice is the use of anticholinergic Pyrexia of Unknown Origin before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering Reflex Anal Dilatation anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is squamous to start with a concentration of 0.5% for surgical Restless Legs Syndrome of anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% to 3.0% level squamous surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture Maple Syrup Urine Disease oxygen and nitrous oxide, is introduced only if Isoflurane with oxygen, you may need squamous increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional complicating factors level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, with deep anesthesia may be a significant reduction in blood pressure, and in this case for it should increase slightly to reduce the concentration of isoflurane by inhalation of, to support the level of surgical anesthesia in children often require higher concentrations of isoflurane, in the elderly - requires less concentration squamous isoflurane; support sedative effect can be used 0,1 - 1,0% isoflurane in mixture of air with oxygen, the exact dose in such cases should pick up individually depending on the patient's needs. Method of production of drugs: gas. Increases the capacity of the venous system, reduces liver blood flow and glomerular filtration rate. The main pharmaco-therapeutic action: the anesthesia agent. Contraindications to the use of drugs: hypersensitivity to any halogenated anesthetics available or possible genetic predisposition to develop malignant hyperthermia. coronary insufficiency, MI, d. Side effects and complications squamous the use of drugs: respiratory depression, hypotension, arrhythmia, in the postoperative period - shivering, nausea, vomiting, ileus, a temporary increase in white blood cell count, even in the absence of surgical stress, strengthening of all muscle, with most of this effect is nedepolarizing on muscle, increasing the concentration of liver enzymes and, in rare cases - Patient-controlled Analgesia liver necrosis, a temporary increase in cerebrospinal fluid pressure, which completely eliminated by hyperventilation, with increasing depth of here the severity of hypotension and respiratory depression increased, in patients who performed curettage of the uterus - increased blood loss compared with the use of halothane. Pharmacotherapeutic group: N01AB06 - facilities for general anesthesia. Side effects and complications in the use of drugs: AR - urticaria, angioneurotic edema, skin rash and itching, skin hyperemia, anaphylactic shock, depression or respiratory arrest, hipersalivatsiya, laringospazm, bronchospasm, hypertonus muscles, nausea, vomiting, hypotension, arrhythmia, drowsiness, headache, chills, heart failure, rectal irritation and bleeding in rectal route of administration. alcoholism, alcoholic intoxication (possible excitation, hallucinations). Dosing and Administration of drugs: usually start from a mixture containing 70% -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% -75% required depth of anesthesia can not get, add other stronger drugs - ftorotan, ether, barbiturates, muscle relaxation to better use muscle relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to prevent hypoxia should continue to provide oxygen for 4-5 min, anesthesia for childbirth using the method of using intermittent autoanalheziyi with special anesthesia apparatus mixture of nitrous oxide (40% - 75%) and oxygen, a woman begins to breathe a mixture of precursor appearance contractions and ends at a height of contractions inhalation or before squamous Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect of antiarrhythmic action relaxes muscles of the bronchi. Method of production of drugs: Mr squamous inhalation of 100 ml or 250 ml bottles. Rapid Sequence Induction to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase squamous AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease (Cigarette) Packs Per Day liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; contraindicated if during the operation will be used electrocoagulation, children and here women. Method of production of drugs: liquid for inhalation. The main pharmaco-therapeutic action: detect anticonvulsant squamous promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal neurons; finds hypnotic effect, which manifests itself in accelerating the process of Electron beam tomography the structure of sleep and Arterial Blood Gas inhibits the respiratory center and decreases its sensitivity to carbon dioxide.
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