Checksum with Desalination

Indications for use drugs: City promiyelotsytarnyy leukemia to remission induction. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces differentiation and inhibits proliferation of transformed cells of hematopoiesis, including at miyeloleykozi in humans, the mechanism of action of G promiyelotsytarnomu leukemia (HPML) is to change the link transretynoyevoyi acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein PML. Method of production of drugs: cap. Dosing and Administration of drugs: daily dose of 45 mg/m2 orally, in two adults (8 cap.) For children is the same dose (45 mg/m2), if there are no serious toxic effects (eg, unbearable headache ) treatment should continue 30 to 90 days to achieve complete remission, after which the graduate scheme of consolidation chemotherapy, and if remission occurred in monotherapy, modify dose chemotherapy connecting not necessary in renal or liver failure should reduce the dose to 25 mg/m2. Indications for use minus h.limfoblastnyy leukemia in children and adults, Non-Hodgkin's lymphoma in children. Method of production of drugs: cap. 50 mg № 50. Contraindications to the use of drugs: City, life-threatening complication of thrombocytosis, severe degree of liver failure.